Application of Bioinformatics in Microbial Structural Genomics

The structural genomics project aims at determination of the 3D structure of all proteins experimentally and theoretically. Structural information of a protein is valuable in functional annotation and powerful in new drug-discovery. Another goal is to provide at least a representative structure for each protein family. Sequence and structure data will be combined using bioinformatics methods (a) to compare the known data in the database, (b) to predict and analyze targets, (c) help target selection, (c) and to provide a platform to communicate and coordinate.

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